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Montelukast (Singulair) is a drug that relieves allergy symptoms and is also used to prevent asthma attacks. Singulair has an average rating of 6. Singulair can also provide relief for seasonal, indoor, and outdoor allergies. Singulair is used for allergies, only after other treatments have failed Side Effects off Singulair Overall, Singular is a safe medicine, but side effects may occur. A generic is considered to be as safe and effective as the original drug. It is usually an add-on treatment for asthma that is difficult to control. Singulair is a remote possibility for treating a pet dog’s allergies, but it’s also a potentially dangerous medication. Some common negative effects are: 6 Skin rash Mood changes Headache or dizziness Stomach pain Heartburn or indigestion Nausea, diarrhea, or constipation Toothache or infection Ear pain or infection Muscle weakness Conjunctivitis (pink eye) Fatigue. For Allergic Rhinitis: “Singulair worked great for my non allergic rhinitis and sinus. 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